PREVALENCE OF DRUG RESISTANCE TO FIRST LINE DRUGS AMONG TUBERCULOSIS PATIENTS IN ASTANA
| Autor: | Z. K. Rakisheva, G. S. Balasanyants, A. S. Akisheva, A. B. Tsepke, N. S. Solovieva |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Туберкулез и болезни лёгких, Vol 96, Iss 8, Pp 50-54 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2075-1230 2542-1506 |
| DOI: | 10.21292/2075-1230-2018-96-8-50-54 |
| Popis: | The objective of the study: to study the prevalence of resistance to first line drugs among tuberculosis patients in Astana (Kazakhstan Republic).Subjects and methods. Data on resistance to first line drugs according to the WHO classification were analyzed, they included sputum test results of 449 patients with bacillary excretion who received in-patient treatment in TB Dispensary in Astana in 2017. Bactec and Hain test were used for drug susceptibility testing.Results. The study showed that among new tuberculosis patients and relapses, resistance to isoniazid (H) dominated and made 87.4% (76 out of 87) and 91.1% (41 out of 45) of cases respectively. Resistance to H was registered more often versus resistance to streptomycin. H-resistant strains were detected confidently more often than rifampicin resistance: 76/226 (33.6%) versus 18/226 (8.0%) among all new cases (p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|