| Autor: |
Rajani Kadri, Namrata Sasalatti, Sudhir Hegde, Ajay A Kudva, Devika Parameshwar, Akansha Shetty |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Kerala Journal of Ophthalmology, Vol 33, Iss 1, Pp 56-60 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
0976-6677 |
| DOI: |
10.4103/kjo.kjo_91_20 |
| Popis: |
Purpose: To evaluate the morphological features of corneal endothelium and central corneal thickness (CCT) in patients with type 2 diabetes mellitus (DM) and to correlate them with the duration of diabetes and patients glycemic status. Design: This was a prospective, cross-sectional, comparative, hospital-based study. Materials and Methods: The present study was conducted on 192 diabetics and 192 age- and sex-matched healthy controls. Corneal endothelial cell characteristics, CCT were measured using a specular microscope. Statistical comparisons were done between the case and controls using the appropriate parametric or nonparametric test. The associations between the various parameters were studied using the Pearson coefficient of correlation. Results: The mean corneal endothelial cell density (CECD) in the diabetic group (2521.3 ± 300.7 cells/mm2) was significantly lower compared to the nondiabetic group (2629.3 ± 221 cells/mm2) ( P < 0.001). The mean CCT in diabetic group was significantly higher (532.00 ± 24.88 μm) compared to control group (499.47 ± 24.76 μm) ( P < 0.001). The co-efficient of variation though higher and hexagonality though lower in diabetics was not statistically significant. CCT showed a significant positive correlation with duration of DM (r = 0.566, P10 years when compared with those with a duration of |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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