A modern understanding of the surfactant protein mutations role in the formation of interstitial lung diseases in newborns and infants
| Autor: | O.L. Logvinova, M.A. Gonchar |
|---|---|
| Jazyk: | English<br />Ukrainian |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Zdorovʹe Rebenka, Vol 13, Iss 5, Pp 516-523 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2224-0551 2307-1168 |
| DOI: | 10.22141/2224-0551.13.5.2018.141570 |
| Popis: | The article presents a modern understanding of the components of the surfactant, the functions of non-serum proteins SP-A, SP-B, SP-C and SP-D. The history of the discovery of protein deficiencies SP-B, SP-C and ABCA3 is described. The authors had analyzed modern epidemiology, clinical and histological features of various deficiencies of surfactant proteins. Various variants of SFTPC, SFTPB and ABCA3 mutations and their influence on the course, clinical manifestations and outcome of interstitial lung disease in children are demonstrated. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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