| Autor: |
Diem Thu Nguyen, David Marancik, Esteban Soto |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Fish and Shellfish Immunology Reports, Vol 3, Iss , Pp 100067- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2667-0119 |
| DOI: |
10.1016/j.fsirep.2022.100067 |
| Popis: |
Flavobacterium columnare represent one of the most important bacterial pathogens of cultured sturgeon. However, at present there are no commercially available vaccines to prevent infection and treatment options are limited. β-glucans have been shown to be potent immunostimulants that can provide fish protection against infectious disease. In this study, the effects of dietary β-glucan supplementation on disease susceptibility were examined by exposing 0.3% β-glucan-fed white sturgeon (Acipenser transmontanus) to Flavobacterium columnare in laboratory-controlled challenges. Morbidity and mortality were monitored for 15 days post-challenge (dpc). Additionally, transcript levels for pro-inflammatory cytokines, regulatory cytokines and acute phase proteins (APP) were investigated in the spleen and gills at different time points post-challenge. No evidence of protection was observed in β-glucan-fed fish challenged with the bacteria. Moreover, significantly greater mortalities were observed in β-glucan-fed fish challenged with F. columnare (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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