Relation between eardrum flap area and healing outcome of traumatic eardrum perforation

Autor: LOU Zheng-cai, TANG Yong-mei, WU Xiao-hong, CHEN Jia-hai
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Chinese Journal of Traumatology, Vol 14, Iss 5, Pp 264-269 (2012)
Druh dokumentu: article
ISSN: 1008-1275
Popis: 【Abstract】Objective: To retrospectively study the clinical effects of eardrum flap area on the healing outcome following traumatic perforation. Methods: Totally 291 traumatic eardrum perforations with in-/everted edges were included in this study. They were randomly divided into three groups and received conservative treatment, epidermal growth factor (EGF) via Gelfoam patching, or edge-approximation plus Gelfoam patching respectively. Patients in each group were further divided into two subgroups according to the eardrum flap area≤1/2 or >1/2 of the perforation size. The healing rate and mean closure time after tympanic membrane perforation were evaluated at three months. Results: Of the total 291 participants, 281 were included in the final statistical analysis. The area of curled edge did not affect the healing outcome significantly in any groups (P>0.05). The healing rate varied slightly: 90.7% vs 92.3% in spontaneous healing group, 98.2% vs 97.4% in EGF via Gelfoam patching group, and 96.5% vs 100% in edge-approximation plus Gelfoam patching group. In addition, in all groups the area of curled edge did not affect the mean closure time significantly (P>0.05). The closure time was (32.3?.4) d vs (30.6?.1) d in sponaneous healing group, (13.4?.5) d vs (13.1?.9) d in EGF via Gelfoam patching group, and (11.9?.1) d vs (12.2?.1) d in edge-approximation plus Gelfoam patching group. Conclusion: The eardrum flap area of traumatic eardrum perforation does not significantly affect the clinical outcomes. Key words: Tympanic membrane perforation; Wounds and injuries; Surgical flaps; Gelatin sponge, absorbable
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