Porcine skin ablation using mid-infrared picosecond pulse burst

Autor: Wenjie Yue, Yongchang Zhang, Libing Shi, Tao Chen, Jianmin Chen, Bo Wu, Songying Zhang, Rong Shu, Yonghang Shen
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Results in Optics, Vol 9, Iss , Pp 100309- (2022)
Druh dokumentu: article
ISSN: 2666-9501
DOI: 10.1016/j.rio.2022.100309
Popis: We present the porcine skin ablation using a mid-infrared high-repetition-rate picosecond pulse burst laser. A burst-mode pulse with a repetition rate of 16.32 MHz was generated from a home-built difference frequency generation (DFG) system operating at 3 μm. Within each burst, there were 16 equally spaced 8.5 ps sub-pulses at an intra-burst repetition rate of ∼3.3 GHz. To study the laser-tissue interaction, laser powers of 1 to 2 W, and scanning times from 1 to 10 with spot size of ∼50 μm were applied to irradiate the fresh porcine skin. The results demonstrate that the burst-mode pulse with modest peak power density of MW/cm2 is efficient for tissue ablation. The optimized ablation depth increased with the average power and scanning times, reaching a maximal incision depth of 150 μm. Thanks to the high repetition rate of intra-burst pulse and high absorption of radiation, the ablation width and thermal effect width kept within 50 μm and 25 μm in all control groups. It is believed that as the first demonstration, such mid-infrared burst-mode laser radiation with modest power intensity is of great potential to realize micron penetration depth and low thermal effect in high-precision surgery applications.
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