Relationship between age and bronchodilator response at diagnosis in adult-onset asthma

Autor:	Minna Tommola, Ha-Kyeong Won, Pinja Ilmarinen, Heewon Jung, Leena E. Tuomisto, Lauri Lehtimäki, Onni Niemelä, Tae-Bum Kim, Hannu Kankaanranta
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Adult-onset Asthma Cohort study Bronchodilator response Asthma-COPD overlap Spirometry Diseases of the respiratory system RC705-779
Zdroj:	Respiratory Research, Vol 21, Iss 1, Pp 1-9 (2020)
Druh dokumentu:	article
ISSN:	1465-993X
DOI:	10.1186/s12931-020-01441-w
Popis:	Abstract Background Possible variation in bronchodilator response (BDR) according to age at the diagnosis of adult-onset asthma is unknown. Our aim was to assess if BDR in FEV1 is related to age at diagnosis of adult-onset asthma and how many subjects fulfill the 400 mL criterion of BDR, the suggested cut-off for asthma-like reversibility in asthma-COPD overlap (ACO). Methods A total of 1030 patients with adult-onset asthma were included; 245 from SAAS (Seinäjoki Adult Asthma Study, Finland) and 785 from COREA (Cohort for Reality and Evolution of Adult Asthma in Korea) cohorts. BDR in FEV1 at the diagnosis of asthma was assessed. Patients were divided into groups based on age at asthma diagnosis:
Databáze:	Directory of Open Access Journals
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