| Autor: |
Pontus Mertsch, MD, Jeremias Götschke, MD, Julia Walter, PhD, Carlo Mümmler, MD, Alessandro Ghiani, MD, Ulrike Schürmann, Rosemarie Kiefl, Rudolf Maria Huber, MD, Jürgen Behr, MD, Nikolaus Kneidinger, MD, PhD, Katrin Milger, MD |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
World Allergy Organization Journal, Vol 15, Iss 10, Pp 100698- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1939-4551 |
| DOI: |
10.1016/j.waojou.2022.100698 |
| Popis: |
Background: Due to the effects of climate change, winter sport enthusiasts will be increasingly forced to stay at higher altitudes. High altitude (HA) environmental factors such as cold temperature, physical exertion, and hypoxia with subsequent hypocapnia due to hyperventilation have been shown to induce bronchoconstriction. With bronchial asthma being highly prevalent, asthmatics also will be increasingly exposed to HA environment and might experience increasing symptoms. Methods: We analysed the effects of HA factors at around 2600 m a.s.l. (metres above sea level) on lung function in mild seasonal asthmatics while they were routinely off (January) and on (March, after start of lowland pollen season) low-dose inhaled corticosteroid (ICS) treatment (n = 10), and matched healthy controls (n = 11). Results: Without inhaled corticosteroid (ICS) treatment mean FEV1 in asthmatics was 230 ml lower after exercise at HA compared to low altitude (LA, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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