Trends in surgical management of spinal metastases in a Singaporean tertiary referral center: a 17-year retrospective review

Autor: Jiong Hao Jonathan Tan, James Thomas Patrick Decourcy Hallinan, Renick Lee, Yiong Huak Chan, Tuan Hao Tan, Shi Wei Ang, Le Tian Isaac Tan, Joelle Hwee Inn Tan, Qinxiang Shant Sin, Dennis Hwee Weng Hey, Leok Lim Lau, Joseph Thambiah, Hee Kit Wong, Gabriel Liu, Naresh Kumar
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Oncology, Vol 13 (2023)
Druh dokumentu: article
ISSN: 2234-943X
DOI: 10.3389/fonc.2023.1297553
Popis: IntroductionSurgical treatment is increasingly the treatment of choice in cancer patients with epidural spinal cord compression and spinal instability. There has also been an evolution in surgical treatment with the advent of minimally invasive surgical (MIS) techniques and separation surgery. This paper aims to investigate the changes in epidemiology, surgical technique, outcomes and complications in the last 17 years in a tertiary referral center in Singapore.MethodsThis is a retrospective study of 383 patients with surgically treated spinal metastases treated between January 2005 to January 2022. Patients were divided into 3 groups, patients treated between 2005 – 2010, 2011-2016, and 2017- 2021. Demographic, oncological, surgical, patient outcome and survival data were collected. Statistical analysis with univariate analysis was performed to compare the groups.ResultsThere was an increase in surgical treatment (87 vs 105 vs 191). Lung, Breast and prostate cancer were the most common tumor types respectively. There was a significant increase in MIS(p
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