Gelatin-Coated Magnetic Nanowires for High-Sensitivity Optical Labels

Autor: M. Charbel Cuevas-Corona, J. Mauricio Lopez-Romero, Alejandro Manzano-Ramírez, Rodrigo Esparza, Rosa E. Zavala-Arce, Alejandro J. Gimenez, Gabriel Luna-Bárcenas
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nanomaterials, Vol 13, Iss 1, p 15 (2022)
Druh dokumentu: article
ISSN: 2079-4991
DOI: 10.3390/nano13010015
Popis: The encapsulation of magnetic nickel nanowires (NiNWs) with gelatin is proposed as an alternative for optical label detection. Magnetic nanowires can be detected at very low concentrations using light-scattering methods. This detection capacity could be helpful in applications such as transducers for molecular and biomolecular sensors; however, potential applications require the attachment of specific binding molecules to the nanowire structure. In the present study, a method is presented which is helpful in coating magnetic nanowires with gelatin, a material with the potential to handle specific decoration and functionalization of the nanowires; in the first case, silver nanoparticles (AgNPs) are efficiently used to decorate the nanowires. Furthermore, it is shown that the synthesized gelatin-coated particles have excellent detectability to the level of 140 pg/mL; this level of detection outperforms more complex techniques such as ICP-OES (~3 ng/mL for Ni) and magnetoresistance sensing (~10 ng/mL for magnetic nanoparticles).
Databáze: Directory of Open Access Journals