| Autor: |
Natasha Hansraj, Anca Safta, Samuel M. Alaish |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Journal of Pediatric Surgery Case Reports, Vol 3, Iss 12, Pp 566-569 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
2213-5766 |
| DOI: |
10.1016/j.epsc.2015.09.014 |
| Popis: |
Juvenile polyposis coli (JPC) is a rare hereditary disorder in which patients have multiple polyps in the gastrointestinal tract and present most commonly with hematochezia. We describe a 4-year-old with intermittent rectal prolapse presenting with altered mental status and headaches. JPC was diagnosed by the presence of multiple, pedunculated, colonic polyps on colonoscopy; his altered mental status resulted from cerebral venous sinus thrombosis. Although JPC is known to be associated with a protein losing enteropathy (PLE), this usually manifests as merely hypoalbuminemia and protein losses without major clinical sequelae. We present a rare complication of cerebral venous sinus thrombosis which highlights altered mental status as a rare presentation of JPC. To our knowledge, this is the first case report in the literature linking JPC, decreased protein S activity, a single mutation in the methylenetetrahydrofolate reductase gene and cerebral thrombosis. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
