Cardiac left ventricular myocardial tissue density, evaluated by computed tomography and autopsy

Autor: Alexandra G. Gheorghe, Andreas Fuchs, Christina Jacobsen, Klaus F. Kofoed, Rasmus Møgelvang, Niels Lynnerup, Jytte Banner
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Medical Imaging, Vol 19, Iss 1, Pp 1-9 (2019)
Druh dokumentu: article
ISSN: 1471-2342
DOI: 10.1186/s12880-019-0326-4
Popis: Abstract Background Left ventricular mass (LVM) is an independent risk factor for the prediction of cardiac events. Its assessment is a clinically important diagnostic procedure in cardiology and may be performed by Computed Tomography (CT). The aim of this study was to assess the correlation between the cardiac left ventricular shell volume (LVShV) determined by postmortem Computed Tomography (PMCT) and the anatomic LVM obtained at autopsy and to calculate the myocardial tissue density. Methods A total of 109 deceased individuals were examined with a 64-slice CT scanner and LVShV was determined. At autopsy, the left ventricle was dissected and weighted. The correlation between LVShV and the anatomic LVM was analysed. Asymmetric left ventricular (LV) hypertrophy was recorded. Inter-observer variability was evaluated, and a density value for myocardial tissue was calculated. Results The mean age of the deceased was 55 ± 16 years, and 58% was men. We found 30 cases of asymmetric LV hypertrophy. A highly positive correlation existed between LVShV and anatomic LVM (r = 0.857; p
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