| Autor: |
Pham Huong Quynh, Tran Thi Thuy Ninh, Nguyen Quang Tinh, Nguyen Van Thu, Dang Van Thanh, Duc Dung Nguyen, Cao Thanh Hai, Khieu Thi Tam |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Materials Research Express, Vol 11, Iss 7, p 075002 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2053-1591 |
| DOI: |
10.1088/2053-1591/ad5c2f |
| Popis: |
The green synthesis of inorganic nanoparticles using plant extracts has been an important strategy to mitigate the uses of hazardous chemicals and thus reduce toxic by-products. We herein report for the first time the synthesis of silver nanoparticles (AgNPs) utilizing Vitis heyneana fruit peel as a key agent. Specifically, oleanolic acid was found in the extract and its crucial role as both reducing and stabilizing agent was experimentally evidenced. The as-synthesized AgNPs were morphologically and structurally characterized to possess quasi-spherical shapes with an average diameter of 11 nm and exhibit polycrystalline nature. Bioactive studies indicated that as-synthesized AgNPs revealed potent antimicrobial activities against Lactobaccillus plantarum , Pseudomonas aeruginosa , and Aspergillus flavus, demonstrating an IC _50 value of 20.00 ± 2.05 μ g ml ^−1 and a MIC value of 32 ± 0.03 μ g ml ^−1 (against Pseudomonas aeruginosa ); the NPs also possessed superior antioxidant activities with an IC _50 value of 23.22 ± 1.25 μ g ml ^−1 compared to vitamin C (18.23 ± 0.15 μ g ml ^−1 ). The AgNPs further revealed capabilities of colorimetrically detecting Hg ^2+ ions with a limit of detection of 0.048 μ M and a limit of quantitation of 0.16 μ M. These findings therefore suggest promising uses of the phytosynthesized AgNPs in nanomedicine and sensing technology. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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