The Mouse Superior Colliculus: An Emerging Model for Studying Circuit Formation and Function

Autor: Shinya Ito, David A. Feldheim
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Frontiers in Neural Circuits, Vol 12 (2018)
Druh dokumentu: article
ISSN: 1662-5110
DOI: 10.3389/fncir.2018.00010
Popis: The superior colliculus (SC) is a midbrain area where visual, auditory and somatosensory information are integrated to initiate motor commands. The SC plays a central role in visual information processing in the mouse; it receives projections from 85% to 90% of the retinal ganglion cells (RGCs). While the mouse SC has been a long-standing model used to study retinotopic map formation, a number of technological advances in mouse molecular genetic techniques, large-scale physiological recordings and SC-dependent visual behavioral assays have made the mouse an even more ideal model to understand the relationship between circuitry and behavior.
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