| Autor: |
Aissatou Diagne, Babacar Souleymane Sambe, Folly Mawulolo Gaba, Ibrahima Sarr, Arona Sabène Diatta, Ousmane Sadio, Serigne Ousmane Mbacké Diaw, Hélène Ataume Mawounge Diatta, Babacar Diouf, Inès Vigan-Womas, Babacar Mbengue, Makhtar Niang |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Tropical Medicine and Health, Vol 52, Iss 1, Pp 1-8 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1349-4147 |
| DOI: |
10.1186/s41182-024-00655-8 |
| Popis: |
Abstract In malaria endemic countries, non-falciparum species are often mixed with Plasmodium falciparum in patients with uncomplicated malaria, and their contribution to malaria severity and death is poorly studied. This study assesses the contribution of non-falciparum species to malaria severity in three regions of Senegal with the highest malaria incidence. We analysed 617 blood samples obtained between 2015 and 2021 from confirmed malaria patients at health facilities in Kedougou, Kolda and Tambacounda in Senegal. Plasmodium species composition was determined by PCR and their distribution were analysed according to age and disease severity, and the relative risk of developing severe malaria. Overall, 94.8% of samples contained P. falciparum either as single or mixed with other species. Non-falciparum P. ovale, P. vivax and P. malariae species were detected in 60.12, 13.61 and 1.62% of samples, respectively. Severe malaria was primarily due to P. falciparum, but co-infection with P. vivax led to a 1.63-fold significant (p = 0.05) increased risk of developing severe malaria, contrasting with the non-significant reduced risk (OR = 0.78; CI 95: 0.55–1.11; p = 0.16) associated with P. ovale infections. Children aged |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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