Plasmablastic Lymphoma: Case Report of Prolonged Survival of an Advanced Human Immunodeficiency Patient and Literature Review

Autor:	Hind Rafei, Ehab El-Bahesh, Antoine Finianos, Min-Ling L. Liu, Geraldine P. Schechter
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Case Reports in Hematology, Vol 2017 (2017)
Druh dokumentu:	article
ISSN:	2090-6560 2090-6579
DOI:	10.1155/2017/9561013
Popis:	Clinical Practice Points. Plasmablastic lymphoma (PBL) is a rare and highly aggressive variant of diffuse large B cell lymphoma with median survival of advanced stage patients varying between 6 and 15 months in previous reports. We report here a human immunodeficiency virus-infected patient surviving over 12 years following treatment for advanced PBL with EPOCH chemotherapy and intrathecal therapy. This case highlights the potential for improved survival in PBL with intensive chemotherapy. Further, literature review suggests promising prospects utilizing novel targeted therapies to increase the rate of prolonged responses.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/f0e783b529f74f2385f5ce05ebddfd85 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF