Third-generation rabies viral vectors have low toxicity and improved efficiency as retrograde labeling tools

Autor: Lindsay A. Schwarz
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cell Reports: Methods, Vol 3, Iss 11, Pp 100646- (2023)
Druh dokumentu: article
ISSN: 2667-2375
DOI: 10.1016/j.crmeth.2023.100646
Popis: In this issue of Cell Reports Methods, Jin et al. report the generation and validation of a rabies variant, RVΔL, for projection-based neuronal labeling. RVΔL shows little toxicity in vivo and has an improved growth advantage over another variant, RVΔGL, making it a useful tool for a wide variety of systems neuroscience-based studies.
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