| Autor: |
Eric J Ley, Navpreet K Dhillon, Yassar M Hashim, Naomi Berezin, Felix Yong, Geena Conde, Russell Mason |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Trauma Surgery & Acute Care Open, Vol 6, Iss 1 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2397-5776 |
| DOI: |
10.1136/tsaco-2021-000686 |
| Popis: |
Background We sought to compare enoxaparin dosing for venous thromboembolism (VTE) prophylaxis in trauma patients with and without traumatic brain injury (TBI) to better understand the time and dose required to reach target anti-Xa levels. Our hypothesis was that patients with TBI have significant delays in the initiation of adequate pharmacological prophylaxis and require a higher enoxaparin dose than currently recommended.Methods The medical records of trauma patients who received enoxaparin dosing based on anti-Xa trough levels between August 2014 and October 2016 were reviewed. Patients were included if their anti-Xa trough level reached the target range (0.1 IU/mL to 0.2 IU/mL).Results A total of 163 patients had anti-Xa levels within the target range of which 41 (25.2%) had TBI. Patients with TBI had longer delays before initiating enoxaparin (7.5 days vs. 1.5 days after admission, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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