Cutaneous graft-versus-host disease after hematopoietic stem cell transplant - a review

Autor: Cesar Daniel Villarreal Villarreal, Julio Cesar Salas Alanis, Jose Carlos Jaime Pérez, Jorge Ocampo Candiani
Jazyk: English<br />Portuguese
Rok vydání: 2016
Předmět:
Zdroj: Anais Brasileiros de Dermatologia, Vol 91, Iss 3, Pp 336-343 (2016)
Druh dokumentu: article
ISSN: 0365-0596
1806-4841
DOI: 10.1590/abd1806-4841.20164180
Popis: Abstract Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease. This review focuses on the pathophysiology, clinical features, prevention and treatment of cutaneous graft-versus-host disease. We discuss various insights into the disease's mechanisms and the different treatments for acute and chronic skin graft-versus-host disease.
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