The risk and severity of stroke in patients with atrial fibrillation and gout: A National Representative Database study

Autor: Faris Haddadin, Ana B. Arevalo, Ahmad Jabri, Hassan Beydoun, Farah Fram, Alba Munoz Estrella, Saima Karim, Salim Virani, Yousaf Ali
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Arrhythmia, Vol 37, Iss 2, Pp 394-399 (2021)
Druh dokumentu: article
ISSN: 1883-2148
1880-4276
DOI: 10.1002/joa3.12505
Popis: Abstract Background It has been shown that gout is associated with left atrium remodeling and a pro‐inflammatory state leading to the development of atrial fibrillation (AF). There is limited evidence whether gout increases the risk of stroke in patients with AF. We assessed the incidence of gout and the risk of stroke in patients with AF. Methods This is a retrospective cohort study using the 2016 US National Inpatient Sample (NIS) based on ICD‐10 codes. The outcomes of the study were the risk and severity of new stroke in patients with pre‐existing AF and gout. Results In 2016, we identified 3 844 057 patients admitted to the hospitals in NIS with history of AF, of which 240 875 had history of gout. Patients with AF and gout have higher risk of new stroke (OR 2.07 [1.97‐2.19], P
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