The Successful Treatment of a Case of Linear Psoriasis with Ixekizumab

Autor: Sara Ghoneim, Alvaro J. Ramos-Rodriguez, Fernando Vazquez de Lara, Lauren Bonomo
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Case Reports in Dermatological Medicine, Vol 2017 (2017)
Druh dokumentu: article
ISSN: 2090-6463
2090-6471
DOI: 10.1155/2017/3280215
Popis: Linear psoriasis is an unusual clinical variation of psoriasis that manifests segmentally along the lines of Blaschko. A major differential diagnosis is inflammatory linear verrucous epidermal nevus (ILVEN). The treatment of linear psoriasis is often challenging, with inadequate response to biological agents reported in the literature. We report a case of a 25-year-old African-American female who presented with asymptomatic hyperkeratotic papules along the lines of Blaschko and was subsequently diagnosed with linear psoriasis. After failing conventional treatment regimens, the patient received a trial of ixekizumab with complete resolution of cutaneous lesions reported after 4 months and only 8 doses of the anti-IL-17 biologic agent.
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