Concomitant administration of meningococcal vaccines with other vaccines in adolescents and adults: a review of available evidence
Autor: | Justine Alderfer, Amit Srivastava, Raul Isturiz, Cynthia Burman, Judith Absalon, Johannes Beeslaar, John Perez |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: | |
Zdroj: | Human Vaccines & Immunotherapeutics, Vol 15, Iss 9, Pp 2205-2216 (2019) |
Druh dokumentu: | article |
ISSN: | 2164-5515 2164-554X 21645515 |
DOI: | 10.1080/21645515.2019.1581542 |
Popis: | Invasive meningococcal disease (IMD), a rapidly progressing and potentially fatal illness, disproportionately affects adolescents and young adults. While IMD is best prevented by vaccination, vaccine uptake in these groups is low. An evidence-based understanding of the safety and effectiveness of concomitant vaccination of meningococcal vaccines, including the newer MenB protein vaccines and the more established MenACWY conjugate vaccines, with other vaccines recommended for adolescents and young adults may help maximize vaccination opportunities. We identified 21 studies assessing concomitant administration of meningococcal vaccines with other vaccines in adolescents and adults. Although studies varied in methodology, concomitant administration generally did not affect immunogenicity of the meningococcal or coadministered vaccines. In some cases, reactogenicity increased following concomitant administration, but no definitive safety concerns were raised. In general, data suggest that meningococcal vaccines can be safely and effectively coadministered with other vaccines. |
Databáze: | Directory of Open Access Journals |
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