Factors associated with surgical morbidity of primary debulking in epithelial ovarian cancer
| Autor: | Emre Günakan, Yusuf Aytaç Tohma, Mehmet Tunç, Hüseyin Akıllı, Hanifi Şahin, Ali Ayhan |
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| Jazyk: | English<br />Korean |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Obstetrics & Gynecology Science, Vol 63, Iss 1, Pp 64-71 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2287-8572 2287-8580 |
| DOI: | 10.5468/ogs.2020.63.1.64 |
| Popis: | ObjectiveEpithelial ovarian cancer (EOC) requires an aggressive surgical approach. The important part of literature on ovarian cancer surgery emphasize residual tumor and survival analyses. Morbidity issue keeps in background. Therefore, we aimed to report on morbidity of cytoreductive surgery for EOC in this study.MethodsEOC patients who underwent primary debulking were evaluated. Intraoperative and postoperative complications that occurred within 30 days after the surgery and factors that affect morbidity were considered.ResultsThe study involved 359 patients. Forty-six intraoperative complications occurred in 42 (11.6%) patients. Advanced stage and cancer antigen level of 125 were independently and significantly associated with operative complications (hazard ratio [HR], 1.66; 95% confidence interval [CI], 1.01–2,73; P=0.044, and HR, 1.47; 95% CI, 1.05–2.06; P=0.025, respectively). The need for intensive care unit admission was significantly higher in patients with intraoperative complications (28.6% vs. 8.8%, P=0.001). Intraoperative and postoperative complication rates were significantly higher in extended surgery than in standard surgery (18.9%vs. 8.5%, P=0.005 and 38.7% vs. 10.9%, P |
| Databáze: | Directory of Open Access Journals |
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