Cholestatic liver injury secondary to over-the-counter cyproheptadine: case report and review of literature

Autor:	Ayush Agarwal, Arpit Shastri, C. P. Ganesh, Malvika Shastri, Suvradeep Mitra, Debadrita Ray, Arka De
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Cyproheptadine Drug-induced liver injury Cholestasis Orexigenic Surgery RD1-811 Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Egyptian Liver Journal, Vol 14, Iss 1, Pp 1-5 (2024)
Druh dokumentu:	article
ISSN:	2090-6226
DOI:	10.1186/s43066-024-00333-8
Popis:	Abstract Background Cyproheptadine is an easily available over-the-counter first-generation antihistaminic that is often used as an appetite stimulant. Although it is usually a safe drug, rare instances of drug-induced liver injury may occur. Case presentation We report a case of cholestatic liver injury secondary to cyproheptadine in a young pharmacy student with chronic hepatitis B and review the literature of cyproheptadine-induced liver injury. Conclusion Although cyproheptadine is largely a safe drug, its potential for significant liver toxicity cannot be ignored.
Databáze:	Directory of Open Access Journals
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