CAPABILITIES OF MAGNETIC RESONANCE IMAGING IN THE DETECTION OF METASTATIC LESION OF THE SPINE AND PELVIC BONES IN PATIENTS WITH PERIPHERAL NON-SMALL CELL LUNG CANCER

Autor: A. V. Laryukov, R. Sh. Khasanov, M. K. Mikhaylov, E. K. Laryukova
Jazyk: English<br />Russian
Rok vydání: 2018
Předmět:
Zdroj: Вестник рентгенологии и радиологии, Vol 99, Iss 2, Pp 85-90 (2018)
Druh dokumentu: article
ISSN: 0042-4676
2619-0478
DOI: 10.20862/0042-4676-2018-99-2-85-90
Popis: Objective. To comparatively analyze the diagnostic capabilities of magnetic resonance imaging (MRI) of the spine and pelvic bones with the results of 18F-FDG positron emission computed tomography (PET/CT) and single-photon emission computed tomography (SPECT/CT) in the detection of skeletal metastases in patients with peripheral non-small cell lung cancer (PNSCLC) in order to elaborate optimal approaches to using radiation and nuclear diagnostic techniques.Material and methods. Seventy-one patients with PNSCLC underwent a comprehensive examination of the skeleton regardless of whether they had clinical symptoms of bone lesions. MRI of the spine and pelvic bones, 18F-FDG PET/CT, and SPECT/CT were performed in all the patients with PNSCLC. The investigators analyzed MRI changes in different skeletal parts (cervical, thoracic, lumbar spine, sacrum and pelvic bones) in patients with PNSCLC and compared the findings with the results of a set of radiation and nuclear diagnostic techniques (18F-FDG PET/CT, SPECT/CT). The sensitivity, specificity and diagnostic accuracy of imaging techniques were compared. Clinical cases are presented.Results. 18F-FDG PET/CT is superior to MRI for the detection of metastatic lesions of the spine and pelvic bones. The sensitivity, specificity, and diagnostic accuracy of MRI for the identification of metastases in the spine and pelvic bones were 95.65, 96.8, and 95.85%, respectively. Those of 18F-FDG PET/CT in the detection of bone metastases were 98.7, 99.9, and 99.6%, respectively.Conclusion. 18F-FDG PET/CT is indicated for all patients with PNSCLC to rule out skeletal metastases. It is expedient to perform MRI if there are technical problems with 18F-FDG PET/CT for the detection of metastatic lesion of the spine and pelvic bones.
Databáze: Directory of Open Access Journals
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