Breast Cancer after Radiation Therapy in a Patient with Li-Fraumeni Syndrome: A Case Report

Autor: In Na Yoon, Eun Suk Cha, Jeoung Hyun Kim, Jee Eun Lee, Jin Chung
Jazyk: English<br />Korean
Rok vydání: 2022
Předmět:
Zdroj: 대한영상의학회지, Vol 83, Iss 1, Pp 246-251 (2022)
Druh dokumentu: article
ISSN: 2288-2928
DOI: 10.3348/jksr.2021.0045
Popis: Li-Fraumeni syndrome (LFS) is an inherited autosomal-dominant tumor-predisposition disorder caused by germline mutations in the TP53 tumor suppressor gene. Since patients with LFS are likely to develop therapy-related cancers, radiation therapy should be avoided if breast cancer is found in these individuals. Herein, we present a case of secondary breast cancer in an LFS patient after radiation and chemotherapy for the first diagnosed breast sarcoma.
Databáze: Directory of Open Access Journals