| Autor: |
C.A. Jimenez-Ruiz, J.F. Pascual-Lledó, A. Cícero-Guerrero, M. Cristóbal-Fernández, M. Mayayo-Ulibarri, C. Villar-Laguna |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Pulmonology, Vol 24, Iss 1, Pp 10-15 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2531-0437 |
| DOI: |
10.1016/j.rppnen.2017.10.008 |
| Popis: |
Objective: To analyse the effectiveness and safety of two smoking cessation medications (varenicline and nicotine patches) in patients with controlled psychiatric disorders in daily practice in a Smoking Cessation Service. Methods: This is a retrospective cohort study. It was carried on at a smoking cessation clinic in Madrid and used a convenience sampling strategy. We reviewed medical records of patients diagnosed with psychiatric disorders who attended a Smoking Cessation Service. All patients received similar treatment programme: a combination of pharmacological treatment (varenicline or nicotine replacement therapy) and intensive cognitive-behavioural therapy. Results: The group included 349 patients (38.4% men). Mean age (SD) 49.6 (10.5) years. 28.3 (12.8) cigarettes per day. 156 subjects achieved 9–24 weeks continuous abstinence (44.7%), in 39% of those who used nicotine patches and in 53.7% of those who used varenicline. OR: 1.64 (95% CI: 1.03–2.61; p = 0.036). Success rates were higher in men; OR 1.85 (95% CI: 1.12–3.04; p = 0.016). High levels of CO and high daily cigarette use were associated with poorer success rates (OR: 0.98, 95% CI: 0.96–0.99, p = 0.007; and OR: 0.98, 95% CI: 0.96–1.00, p = 0.045), respectively. Nausea and pruritus were the most common adverse events. No cases of suicidal ideation or behaviour were found. Conclusions: Varenicline and nicotine patches could be safe and effective smoking cessation treatments for patients with psychiatric disorders in daily clinical practice. Keywords: Smoking, Treatment, Psychiatric disorder, Varenicline, Nicotine patch |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
