Clinical significance of Janus kinase inhibitors in the therapy of rheumatoid arthritis: achievements and prospects

Autor: V. I. Mazurov, I. B. Belyaeva
Jazyk: ruština
Rok vydání: 2019
Předmět:
Zdroj: Современная ревматология, Vol 13, Iss 4, Pp 116-123 (2019)
Druh dokumentu: article
ISSN: 1996-7012
2310-158X
DOI: 10.14412/1996-7012-2019-4-116-123
Popis: Significant successes in the use of biological agents (BA) have been achieved in the treatment of rheumatoid arthritis (RA); nonetheless, about 36% of patients cannot respond to therapy or achieve the expected effect. A new area in the treatment of RA is the use of Janus kinase (JAK) inhibitors, targeted synthetic disease-modifying anti-rheumatic drugs (chemical molecules with a molecular weight
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