| Autor: |
Eman Salah Albeltagy, Nashwa Mohamed Abd Elbaky |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Human Nutrition & Metabolism, Vol 27, Iss , Pp 200137- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2666-1497 |
| DOI: |
10.1016/j.hnm.2021.200137 |
| Popis: |
Objectives: Spexin (SPX) is a novel peptide hormone that lowers blood glucose levels and is protective against hepatic steatosis in diet induced obese mouse models. We hypothesized that higher circulating SPX levels would be associated with a lean BMI and a more favorable metabolic profile in humans. We aimed to investigate SPX levels and its association with obesity, glucose metabolic and cardiovascular factors in lean individuals compared to physical activity matched obese individuals. Methods: This cross-sectional study was performed with the participation of 135 individuals with various BMIs. Anthropometric and fasting metabolic parameters were determined in all participants and serum SPX levels were measured using ELISA. Results: The levels of serum SPX were significantly lower in obese individuals than in those with overweight or normal-weight (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
