Amplicon-based sequencing and co-occurence network analysis reveals notable differences of microbial community structure in healthy and dandruff scalps

Autor:	Li Wang, Tao Yu, Yaxin Zhu, Yingfeng Luo, Fan Dong, Xuemei Lin, Wenzhong Zhao, Zilong He, Songnian Hu, Zhiyang Dong
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Scalp Dandruff Microbiota Co-occurrence/co-exclusion network Malassezia sp. Lactobacillus sp Biotechnology TP248.13-248.65 Genetics QH426-470
Zdroj:	BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Druh dokumentu:	article
ISSN:	1471-2164
DOI:	10.1186/s12864-022-08534-4
Popis:	Abstract Background Dandruff is a chronic, recurring, and common scalp problem that is caused by several etiopathogeneses with complex mechanisms. Management of this condition is typically achieved via antifungal therapies. However, the precise roles played by microbiota in the development of the condition have not been elucidated. Despite their omnipresence on human scalp little is known about the co-occurrence/co-exclusion network of cutaneous microbiota. Results We characterized the scalp and hair surface bacterial and fungal communities of 95 dandruff-afflicted and healthy individuals residing in China. The degree distributions of co-occurrence/co-exclusion network in fungi-bacteria and bacteria-bacteria were higher in the healthy group (P
Databáze:	Directory of Open Access Journals
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