Rhodiasolv PolarClean – a greener alternative in solid-phase peptide synthesis
| Autor: | Ashish Kumar, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Green Chemistry Letters and Reviews, Vol 14, Iss 3, Pp 545-550 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1751-8253 1751-7192 17518253 |
| DOI: | 10.1080/17518253.2021.1965663 |
| Popis: | PolarClean, a green solvent prepared through the valorization of a byproduct of Nylon-66 manufacturing, shows an excellent capacity to dissolve all Fmoc-amino acids and key coupling reagents and additives. It can also swell polystyrene and ChemMatrix, the two resins most widely used in solid-phase peptide synthesis. The synthesis of model peptides has been carried out, rendering the target peptide as a major component. The performance of PolarClean demonstrates its utility in the toolbox for Green Solid-Phase Peptide Synthesis. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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