The association of urinary uric acid excretion with ambulatory blood pressure values in patients with chronic kidney disease

Autor: Ying Xu, Xun Zhou, Yuqi Zheng, Haochen Guan, Chensheng Fu, Jing Xiao, Zhibin Ye
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Clinical Hypertension, Vol 26, Iss 1, Pp 1-9 (2020)
Druh dokumentu: article
ISSN: 2056-5909
DOI: 10.1186/s40885-020-0136-6
Popis: Abstract Background To analyze the association between hypertension and urinary uric acid excretion in patients with chronic kidney disease (CKD). Methods We screened 87 patients who had been admitted at the Dept of Nephrology, Huadong hospital between April 2017 to April 2019 who had completed 24-h ambulatory blood pressure monitoring and retained 24-h urine biochemical test specimens, thirty adult patients (age ≤ 65 years) with CKD 1–2 stages were recruited in the study. Pearson’s correlation analysis and multiple linear regression analysis were used to study the correlation of urinary uric acid excretion with ambulatory blood pressure values and the association of morning mean diastolic pressure (mMDP), night mean diastolic pressure (nMDP) and CV of dMSP (coefficient of variation of day mean systolic pressure) with fractional excretion of uric acid (FEua) and uric acid clearance rate (Cur). Independent T test was used to compare the differences of blood pressure values in FEua1 (FEua
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