| Popis: |
In commercial poultry production, chickens are reared under intensive conditions, which may allow infections to spread quickly. Antibiotics are used at sub-therapeutic doses in livestock and poultry feed to prevent diseases and improve productivity. However, restrictions on the use of antibiotics at sub-therapeutic concentrations in livestock feed due to growing concerns of antimicrobial resistance (AMR), together with antibiotic residues in meat and eggs has prompted poultry researchers and feed producers to look for viable alternatives. Thus, there is increasing interest in developing natural alternatives to in-feed antibiotics to improve chicken productivity and health. Probiotics, specifically from the genus Bacillus have proven to be effective due to their spore-forming capabilities. Furthermore, their ability to withstand heat during feed processing and be stored for a long time without losing viability as well as their potential to function in the acidic medium of the chicken gut, provide them with several advantages over conventional probiotics. Several studies regarding the antimicrobial and antioxidant activities of Bacillus probiotics and their positive impact in chicken nutrition have been documented. Therefore, the present review shields light on the positive effect of Bacillus probiotics as alternatives to in-feed antibiotics on growth performance, serum chemistry, antioxidant status, intestinal histomorphology and lesion scores of disease-challenged broiler chickens and the mechanisms by which they exert their actions. It is concluded that Bacillus probiotics supplementation improve growth, health and productive indices of disease-challenged broiler chickens and can be a good alternative to in-feed antibiotics. However, more studies are required on the effect of Bacillus probiotics supplementation in broiler chickens to maximize productivity and achieve the ultimate goal of stopping the usage of antibiotics at sub-therapeutic doses in broiler chicken feed to enhance performance. |
