Abrocitinib: A Comprehensive Review of its Efficacy and Safety in Dermatology

Autor:	Sunil Dogra, Shikha Shah, Manavi Gupta, Ayush Sharma, Seema Chhabra
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	abrocitinib janus kinase jak-stat inhibitor oral small molecule Dermatology RL1-803
Zdroj:	Indian Dermatology Online Journal, Vol 15, Iss 6, Pp 930-941 (2024)
Druh dokumentu:	article
ISSN:	2229-5178 2249-5673
DOI:	10.4103/idoj.idoj_449_24
Popis:	Abrocitinib is a novel oral small molecule which acts as a selective JAK-1 inhibitor. Currently approved for use in moderate-to-severe cases of atopic dermatitis, this drug is gaining a rapid impetus for its use across various inflammatory dermatoses for its selective downstream action on cytokines of the JAK-1 pathway. Its efficacy and safety in atopic dermatitis has been established in phase 3 clinical trials. The future implication of this drug will depend largely on feasibility and practical use in Indian scenario.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/bfcd9a4c5f2e4b3a93c88432724c5ace Zobrazit plný text záznamu View record in DOAJ