Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension

Autor: Alfredo Guillén-Del-Castillo, Manuel López Meseguer, Vicent Fonollosa-Pla, Berta Sáez Giménez, Dolores Colunga-Argüelles, Eva Revilla-López, Manuel Rubio-Rivas, Maria Jose Cristo Ropero, Ana Argibay, Joan Albert Barberá Mir, Xavier Pla Salas, Amaya Martínez Meñaca, Ana Belén Madroñero Vuelta, Antonio Lara Padrón, Luis Sáez Comet, Juan Antonio Domingo Morera, Cristina González-Echávarri, Teresa Mombiela, Norberto Ortego-Centeno, Manuela Marín González, Carles Tolosa-Vilella, Isabel Blanco, Pilar Escribano Subías, Carmen Pilar Simeón-Aznar, RESCLE Consortium, REHAP Consortium
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-022-09353-z
Popis: Abstract To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. Non-PAH-SSc patients from the Spanish SSc registry and PAH-SSc patients from the Spanish PAH registry were included. A total of 364 PAH-SSc and 1589 non-PAH-SSc patients were included. PAH-SSc patients had worse NYHA-functional class (NYHA-FC), worse forced vital capacity (FVC) (81.2 ± 20.6% vs 93.6 ± 20.6%, P
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje