Validity of additional surgical resection by comparing the operative risk with the stratified lymph node metastatic risk in patients with early gastric cancer after endoscopic submucosal dissection

Autor: Hidenori Akaike, Yoshihiko Kawaguchi, Kensuke Shiraishi, Hiroki Shimizu, Shinji Furuya, Naohiro Hosomura, Hidetake Amemiya, Hiromichi Kawaida, Makoto Sudoh, Shingo Inoue, Hiroshi Kohno, Daisuke Ichikawa
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: World Journal of Surgical Oncology, Vol 17, Iss 1, Pp 1-7 (2019)
Druh dokumentu: article
ISSN: 1477-7819
DOI: 10.1186/s12957-019-1679-4
Popis: Abstracts Background Treatment guidelines for early gastric cancer (EGC) recommend additional gastrectomy for lesions which do not achieve curative resection after ESD, due to the potential risk of lymph node metastasis (LNM). However, many cases are found to have no LNMs, and additional gastrectomy itself can be a considerable risk especially in elderly patients. Methods We retrospectively stratified the risk of LNM according to the total number of four LNM risk factors (RFs) that resulted in non-curative resection for ESD in 861 EGC patients who underwent gastrectomy. Next, we compared this stratification risk to the surgical risk based on the National Clinical Database (NCD) risk calculator in 58 patients who underwent additional gastrectomy. Results As the total number of LNM RFs increased, the frequency of LNM also increased significantly (0/1RF 0.76%, 2RFs 15.08%, 3RFs 33.87%, 4RFs 50.00%; p
Databáze: Directory of Open Access Journals
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