Challenges to antimicrobial susceptibility testing of plant-derived polyphenolic compounds

Autor: Bubonja-Šonje Marina, Knežević Samira, Abram Maja
Jazyk: English<br />Croatian
Rok vydání: 2020
Předmět:
Zdroj: Arhiv za Higijenu Rada i Toksikologiju, Vol 71, Iss 4, Pp 300-311 (2020)
Druh dokumentu: article
ISSN: 1848-6312
DOI: 10.2478/aiht-2020-71-3396
Popis: As multidrug resistance gains momentum, the last two decades have seen an ever-growing interest in the antimicrobial properties of plant extracts and plant-derived compounds. Most of the focus is on polyphenols – a large and diverse group of phytochemicals with strong antibacterial activity. Testing methods provide reliable results as long as they follow standard procedures. However, methods and procedures used in antimicrobial susceptibility testing (AST) are often too diverse to allow comparison of results. The lack of uniformity and comparability is much owed to the absence of guidelines. The focus of this review is to give a critical overview of different methods used in the assessment of polyphenols antimicrobial efficacy and to highlight the importance of their standardisation.
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