Extracellular matrix-based biomaterials as adipose-derived stem cell delivery vehicles in wound healing: a comparative study between a collagen scaffold and two xenografts

Autor:	Héctor Capella-Monsonís, Andrea De Pieri, Rita Peixoto, Stefanie Korntner, Dimitrios I. Zeugolis
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Human adipose-derived stem cell delivery Collagen scaffolds Decellularised grafts Wound healing Medicine (General) R5-920 Biochemistry QD415-436
Zdroj:	Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Druh dokumentu:	article
ISSN:	1757-6512
DOI:	10.1186/s13287-020-02021-x
Popis:	Abstract Background Stem cell therapies represent a promising tool in regenerative medicine. Considering the drawbacks of direct stem cell injections (e.g. poor cell localisation), extracellular matrix-based biomaterials (e.g. scaffolds and tissue grafts), due to their compositional biofunctionality and cytocompatibility, are under investigation as potential stem cell carriers. Methods The present study assessed the potential of three commercially available extracellular matrix-based biomaterials [a collagen/glycosaminoglycan scaffold (Integra™ Matrix Wound Dressing), a decellularised porcine peritoneum (XenoMEM™) and a porcine urinary bladder (MatriStem™)] as human adipose-derived stem cell delivery vehicles. Results Both tissue grafts induced significantly (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/bfa5e7b5c2e5414586d56a19e4e594ea Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.