Expression of Pentraxin 3 and Thrombospondin 1 in Gingival Crevicular Fluid during Wound Healing after Gingivectomy in Postorthodontic Patients

Autor: Anne Marie Rauten, Isabela Silosi, Stefan Ioan Stratul, Liliana Foia, Adrian Camen, Vasilica Toma, Daniel Cioloca, Valeriu Surlin, Petra Surlin, Maria Bogdan
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Immunology Research, Vol 2016 (2016)
Druh dokumentu: article
ISSN: 2314-8861
2314-7156
DOI: 10.1155/2016/4072543
Popis: Background. Wound healing is a tissue repair process after an injury, and two of its main components are inflammation and angiogenesis, in which course a cascade of mediators is involved. The aim of this research was to evaluate the involvement of Pentraxin 3 and Thrombospondin 1 in wound healing after periodontal surgery (gingivectomy) for gingival overgrowth during orthodontic treatment with or without magnification devices, by assessing their levels in GCF. Methods. From 19 patients with gingival overgrowth as a result of fixed orthodontic treatment, the overgrown gingiva was removed by gingivectomy, from one half of the mandibular arch without magnification and from the other under magnification. Pentraxin 3 and Thrombospondin 1 were determined from gingival crevicular fluid by ELISA tests. Results. Statistically significant differences (p
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