Von Willebrand factor antigen in systemic lupus erythematosus and antiphospholipid syndrome
| Autor: | A A Novikov, E N Alexandrova, T V Popkova, T M Reshetnyak, N G Klyukvina, D S Novikova, LB Slitivelband, A A Baranov |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2004 |
| Předmět: | |
| Zdroj: | Научно-практическая ревматология, Vol 42, Iss 4, Pp 35-38 (2004) |
| Druh dokumentu: | article |
| ISSN: | 1995-4484 1995-4492 |
| DOI: | 10.14412/1995-4484-2004-799 |
| Popis: | To study clinical significance of von Willebrand factor antigen (WFA) in antiphospholipid syndrome and systemic lupus erythematosus (SLE). Material and methods. Serum concentration of WFA was determined with immune-enzyme assay in 21 pts with primary APS (PAPS), 39 SLE pts with APS, 68 SLE pts and 56 healthy donors. Results. WFA level in PAPS, SLE+APS and SLE was significantly higher than in donors. WFA concentration in serum of SLE pts without APS significantly exceeded that in PAPS. WFA concentration elevation was revealed in 52,4% of PAPS, 56,4% SLE+APS and 73,5% SLE pts. There was no association between WFA level, thromboses and obstetric pathology in PAPS and SLE. WFA concentration increase in SLE with APS correlated with IgM anticardiolipin antibodies and SLEDAI activity index (p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|