Pseudomonas aeruginosa-induced Infections in the Intensive Care Unit

Autor: O. N. Yegorova
Jazyk: English<br />Russian
Rok vydání: 2010
Předmět:
Zdroj: Общая реаниматология, Vol 6, Iss 5 (2010)
Druh dokumentu: article
ISSN: 1813-9779
2411-7110
DOI: 10.15360/1813-9779-2010-5-51
Popis: Objective: to study the regularities of circulation of epidemic Pseudomonas aeruginosa strains in the intensive care unit and to formulate main prophylactic measures against pseudomonas infections. Materials and methods: A prospective epi-demiological observation was made with daily microbiological monitoring of major loci in patients and environmental objects in the intensive care unit for 244 days. A total of 1314 clinical material samples from 888 patients and 488 washes from hospital environmental objects were studied and 211 P.aeruginosa strains were identified by microbiological, serological, and molecular genetic studies. Results. Intensive circulation of epidemic Pseudomonas aeruginosa strains of predominantly O12 serogroup was found in the intensive care unit. The main sources of infection were patients and moist hospital environmental objects; the most important transmission routes are the hands of medical staff and anesthetic respiratory equipment. There was a predominant lesion in the respiratory tract: the incidence of pseudomonas infection was 3.5 times greater than that in the patients on mechanical ventilation equipment. The basic prophylactic measures in the intensive care unit, which are aimed at eliminating P.aeruginosa, should involve daily observation of necessary sanitary-hygienic and antiepidemic rules and organization of care for patients. Conclusion. Prophylactic and antiepidemic measures at hospital should be based on the results of circulating microflora monitoring.
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