Efficacy of Lofexidine in the Outpatient Management of Tramadol Withdrawal Syndrome
| Autor: | Mohammad Majidi, Solmaz Nekoueifard |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | International Journal of Medical Toxicology and Forensic Medicine, Vol 10, Iss 4, Pp 10-4 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2251-8762 2251-8770 |
| DOI: | 10.32598/ijmtfm.v10i4.32270 |
| Popis: | Tramadol is recognized as an opioid with non-opiate properties. It has a low affinity for opioid receptors and prevents reabsorption of norepinephrine and serotonin at synapses. It also increases the level of Gamma Aminobutyric Acid (GABA) in the central nervous system [1, 2]. Tramadol is an analgesic for patients suffering from moderate to severe pain [1]. In addition, previous studies have shown that tramadol abuse and suicidal attempts have increased in Iran [3, 4]. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|