Rathke′s cyst with ectopic neurohypophysis presenting as severe short stature with delayed puberty

Autor:	Deep Dutta, Ajitesh Roy, Sujoy Ghosh, Pradip Mukhopadhyay, Ranen Dasgupta, Satinath Mukhopadhyay, Subhankar Chowdhury
Jazyk:	angličtina
Rok vydání:	2012
Předmět:	Ectopic neurohypophysis multiple pituitary hormone deficiency Rathke′s cyst short stature Diseases of the endocrine glands. Clinical endocrinology RC648-665 Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Indian Journal of Endocrinology and Metabolism, Vol 16, Iss 8, Pp 288-290 (2012)
Druh dokumentu:	article
ISSN:	2230-8210 2230-9500
DOI:	10.4103/2230-8210.104062
Popis:	Ectopic neurohypophysis (EN) is found in nearly half of children with growth hormone deficiency (GHD). Rathke′s cyst (RC) is uncommon in children and when present, hypopituitarism is found in nearly half of them. We present a fourteen and half-year-old girl with severe short stature and delayed puberty who on evaluation was found to have GHD, secondary hypocortisolism, and hypogonadism. Imaging revealed hypoplastic anterior pituitary, stalk agenesis, EN at tuber cinereum and intrapituitary RC. This is perhaps the first report of simultaneous occurrence of EN and RC, which was seen in a girl with multiple pituitary hormone deficiency. A primary defect in pituitary development may explain this simultaneous occurrence of EN and RC and hence this severe anterior pituitary function deficit.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/bf88f139f9534483ab6f42fd58c56d52 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF