Quantification of liver fat deposition in obese and diabetic patients: A pilot study on the correlation with myocardium and periapical fat content

Autor: Xi Chen, Hui-Quan Wen, Qing-Ling Li, Li-Shan Shen, Xiao-Wen Luo, Bin Zhou, Ruo-Mi Guo
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Liver Research, Vol 6, Iss 2, Pp 103-110 (2022)
Druh dokumentu: article
ISSN: 2542-5684
DOI: 10.1016/j.livres.2022.05.005
Popis: Backgroud and aim: Non-alcoholic fatty liver disease (NAFLD) is a worldwide health problem, which associated with systemic health problems and causes a higher risk of all-cause mortality. The leading causes of death in NAFLD patients are cardiac complications followed by NAFLD-related liver complications. This study aimed to quantitatively measure the contents of liver and cardiac fat with varying degrees of NAFLD in an obese group and a type 2 diabetes mellitus (T2DM) group to explore differences and correlations. Materials and methods: This study included 170 patients who underwent echo asymmetry and least square estimation-iron quantification sequencing at 3.0 T magnetic resonance imaging. Fat fraction values were quantitatively measured in regions of interest of the liver, myocardium, and periapical adipose tissue. Results: In both the obese and T2DM groups, cardiac fat content was correlated with liver fat content using linear regression (P
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