Safety and Efficacy of Percutaneous Image-Guided Mediastinal Mass Core-Needle Biopsy

Autor: Patrick J. Navin, MB, BCh, BAO, Nathan L. Eickstaedt, MD, Thomas D. Atwell, MD, Jason R. Young, MD, Patrick W. Eiken, MD, Brian T. Welch, MD, John J. Schmitz, MD, Grant D. Schmit, MD, Matthew P. Johnson, MS, Michael R. Moynagh, MB, BCh
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 5, Iss 6, Pp 1100-1108 (2021)
Druh dokumentu: article
ISSN: 2542-4548
DOI: 10.1016/j.mayocpiqo.2021.09.006
Popis: Objective: To retrospectively evaluate the safety and efficacy of percutaneous image-guided mediastinal mass core-needle biopsy. Patients and Methods: Retrospective review of an institutionally maintained biopsy registry identified 337 computed tomography– or ultrasound-guided percutaneous mediastinal mass core needle biopsies between October 2002 and August 2017 in a single quaternary referral center. Mean patient age was 51 (range, 18 to 93) years. Procedural techniques, anticoagulation/antiplatelet therapy, and tumor anatomical characteristics were reviewed. Classification and gradation of complications was based on the Clavien-Dindo system. Diagnostic yield was defined as the ratio of diagnostic biopsy to all biopsies performed. Results: Mean tumor size was 59.2 (range, 10 to 180) mm with 89.9% (n=303) of lesions located in the prevascular (anterior) mediastinum. There was a single major complication (0.3%) of a symptomatic pneumothorax requiring intervention. There were seven (2.1%) minor complications, including three bleeding complications. A transpleural approach was the only variable associated with an increased complication rate (P
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