Effect of danefukang on symptoms and biomarkers in women with endometriosis

Autor: Yi-cun Zhong, Xiao-fei Zhou, Chun-mei Hou, Wei-ping Li
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Taiwanese Journal of Obstetrics & Gynecology, Vol 58, Iss 2, Pp 218-222 (2019)
Druh dokumentu: article
ISSN: 1028-4559
DOI: 10.1016/j.tjog.2019.01.009
Popis: Objective: The purpose of this study was to observe the efficacy of Danefukang (DEFK) soft extract for the treatment of symptoms associated with endometriosis, and its effect on quality of life, the Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) scores, and on levels of carbohydrate antigen (CA)-125, tumor necrosis factor (TNF)-α, and interleukin (IL)-6. Materials and methods: A total of 174 patients with endometriosis treated from January 2010 to December 2013 were randomly divided into a control group treated with mifepristone (n = 87) or DEFK (n = 87). Both groups were treated for 3 months. Symptoms, quality of life, SAS, SD scores, and levels of CA-125, TNF-α, and IL-6 were evaluated before and after treatment. Results: The effectiveness rate was 93.10% in the DEFK group and 81.61% in the mifepristone control group (χ2 = 4.215, P
Databáze: Directory of Open Access Journals