Emerging frontiers in nanomedicine targeted therapy for prostate cancer

Autor: Tayo Alex Adekiya, Oluwanifemi Owoseni
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cancer Treatment and Research Communications, Vol 37, Iss , Pp 100778- (2023)
Druh dokumentu: article
ISSN: 2468-2942
DOI: 10.1016/j.ctarc.2023.100778
Popis: Prostate cancer is a prevalent cancer in men, often treated with chemotherapy. However, it tumor cells are clinically grows slowly and is heterogeneous, leading to treatment resistance and recurrence. Nanomedicines, through targeted delivery using nanocarriers, can enhance drug accumulation at the tumor site, sustain drug release, and counteract drug resistance. In addition, combination therapy using nanomedicines can target multiple cancer pathways, improving effectiveness and addressing tumor heterogeneity. The application of nanomedicine in prostate cancer treatment would be an important strategy in controlling tumor dynamic process as well as improve survival. Thus, this review highlights therapeutic nanoparticles as a solution for prostate cancer chemotherapy, exploring targeting strategies and approaches to combat drug resistance.
Databáze: Directory of Open Access Journals