Trends in antimicrobial resistance among clinical isolates of Staphylococcus aureus in a university hospital of the north of Paraná from 2002 through 2011
| Autor: | Marcia Regina Eches Perugini, Vitor Hugo Perugini, Ana Rúbia Magalhães Ferreira, Caio Ferreira de Oliveira, Guilherme Teixeira Gomes, Bruna Arantes Rodrigues Lima, Ana Paula Dier Pereira, Floristher Elaine Carrara-Marroni, Eliana Carolina Vespero, Marsileni Pelisson, Maria Alice Galvão Ribeiro |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Semina: Ciências Biológicas e da Saúde, Vol 36, Iss 1Supl, Pp 275-282 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1676-5435 1679-0367 |
| DOI: | 10.5433/1679-0367.2015v36n1Suplp275 |
| Popis: | Staphylococcus aureus are pathogens with high incidence of nosocomial infections and community and has great ability to acquire resistance. The objective of this study was to determine susceptibility to antimicrobial profiles of S. aureus isolated in Londrina University Hospital, from January 2002 through December 2011. The retrospective analysis of 3,494 S. aureus performed from a database of Clinical Laboratory Microbiology HU sector. Antibiotic resistance was judged according to the criteria recommended by the Clinical Laboratory Standards Institute. The highest percentages of resistance was founding to erythromycin (49.4%), clindamycin and oxacillin (41.8%) and ciprofloxacin (36.5%). In addition, there was a significant reduction in gentamicin resistance rates, and trimethoprim-sulfamethoxazol. All strains studied were susceptible to linezolid. We found that 40% showed reduced susceptibility to vancomycin. These data indicate a possible change in the epidemiology of S. aureus in our region, which can bring impact on the treatment and control of infection by this agent. |
| Databáze: | Directory of Open Access Journals |
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