Machine Learning and the Conundrum of Stroke Risk Prediction

Autor: Yaacoub Chahine, Matthew J Magoon, Bahetihazi Maidu, Juan C del Álamo, Patrick M Boyle, Nazem Akoum
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Arrhythmia & Electrophysiology Review, Vol 12, Iss , Pp - (2023)
Druh dokumentu: article
ISSN: 2050-3377
2050-3369
DOI: 10.15420/aer.2022.34
Popis: Stroke is a leading cause of death worldwide. With escalating healthcare costs, early non-invasive stroke risk stratification is vital. The current paradigm of stroke risk assessment and mitigation is focused on clinical risk factors and comorbidities. Standard algorithms predict risk using regression-based statistical associations, which, while useful and easy to use, have moderate predictive accuracy. This review summarises recent efforts to deploy machine learning (ML) to predict stroke risk and enrich the understanding of the mechanisms underlying stroke. The surveyed body of literature includes studies comparing ML algorithms with conventional statistical models for predicting cardiovascular disease and, in particular, different stroke subtypes. Another avenue of research explored is ML as a means of enriching multiscale computational modelling, which holds great promise for revealing thrombogenesis mechanisms. Overall, ML offers a new approach to stroke risk stratification that accounts for subtle physiologic variants between patients, potentially leading to more reliable and personalised predictions than standard regression-based statistical associations.
Databáze: Directory of Open Access Journals