Impact of the impulse electrophoresis of the blood plasma on the wounds healing and formation of cicatricial tissue in experiment
| Autor: | G. V. Terehov, M. V. Chukhraiev, M. V. Kostyliev, S. P. Galych, O. Yu. Furmanov, I. M. Savytska, O. A. Geylenko |
|---|---|
| Jazyk: | Russian<br />Ukrainian |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Клінічна хірургія, Vol 86, Iss 11-12, Pp 69-71 (2019) |
| Druh dokumentu: | article |
| ISSN: | 0023-2130 2522-1396 |
| DOI: | 10.26779/2522-1396.2019.11-12.69 |
| Popis: | Objective. To study in experiment the impact of the impulse electrophoresis of the blood plasma method on the wounds healing process in postoperative wounds. Materials and methods. The investigations were conducted on 15 white rats, to which in aseptic environment under intraabdominal narcosis the hip surgical access through the skin and muscles was conducted with subsequent layered closure of the wound, using separate knots. Ten laboratory animals were included into the main group, in whom transdermal introduction of the blood plasma, using the impulse electrophoresis method, was conducted on the 4th, 7th, 10th and 14th postoperative days. Into a control group 5 white rats were included, in which transdermal introduction of the blood plasma was not applied postoperatively. In all the laboratory animals the wounds have healed primarily. On the19th day postoperatively the laboratory animals were extracted from the experiment, and the near suture skin was investigated, using histological methods. Results. The surgical access healing in the hip skin and muscles with formation of normotrophic cicatrices was observed in the main group of the laboratory animals. Hypertrophic cicatrix in the operative intervention zone have been formatted in the laboratory animals of a control group on the 19th postoperative day. Conclusion. More qualitative healing of the wounds with formation of normotrophic cicatrix while application of transdermal introduction of the blood plasma, using the impulse electrophoresis method, was confirmed in experimental investigation in laboratory animals of the main group. Excessive creation of collagen was omitted in the laboratory animals of the main group, what have promoted formation of more thin and tender cicatrix, which have become slightly visible up to the end of experiment. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|